A total of 43 children with clinical features of rapidly progressive glomerulonephritis were seen at the Department of Pediatric Nephrology from January 1999 to June 2004. Only 29 were included in the study on account of adequacy of data. These patients had biopsy. This is a retrospective cohort study. Medical records of patients with RPGN were reviewed. The patients were followed up during the study period. Demographic data, clinico-pathologic features, treatment modalities and outcome of treatment were analyzed. The mean age of onset of RPGN is 9.6 ± 2.9 years. There were more females than males. Edema, oliguria, gross hematuria, and hypertension were the common clinical features noted. Azotemia, anemia, low C3 levels, elevated ASO were observed in more than half of the patients. Majority of the patients have 50-79% glomeruli with crescents. IV Methylprednisolone, Cyclophosphamide, and Prednisone improved the renal outcome after 1 month and 1 year. There was no statistically significant differences between clinical and laboratory features and pre and post biopsy treatment with histologic findings and treatment outcome. After a year, 88.48% of patients were still alive.