Fungal infections remain a substantial cause of
morbidity and mortality among kidney graft recipients,
although the incidence is less than that reported for other
solid-organ transplant recipients.1 Their occurrence is
mainly related to immunosuppression and noso-comial
hazards.2 Risk factors identified for fungal infections in
this subgroup of patients include the use of high doses
of corticosteroids, multiple or recent rejection episodes,
hyperglycemia, poor transplant function, CMV disease
and leucopenia. There is a 4-fold increase in the risk of
systemic mycoses with the occurrence of CMV disease
and a 2-fold risk with hyperglycemia. Chronic liver
disease increases systematic mycoses 2-fold and older
recipients also increased the risk of fungal infection. |